This report focuses on trends in deaths due to injury and poisoning that occurred over the period 1999–00 to 2014–15. The age-standardised rate of injury deaths decreased from 55.4 to 47.2 deaths per 100,000 between 1999–00 and 2004–05 and changed little after that. Rates for Aboriginal and Torres Strait Islander people were generally at least twice as high as rates for non-Indigenous Australians over the period from 2001–02 to 2014–15.