Summary
Cancer screening involves testing for signs of cancer or precancerous conditions in people without obvious symptoms. The National Cervical Screening Program (NCSP) is one of Australia’s three population-based cancer screening programs. It aims to reduce cervical cancer cases, illness, and deaths by detecting precancerous abnormalities before any potential progression to cervical cancer.
The NCSP is a highly successful public health initiative in Australia, halving cervical cancer incidence and mortality since it was introduced in 1991. This has been achieved through organised, population-based cervical screening to detect precancerous changes, allowing treatment before any progression to cervical cancer, thereby preventing this disease.
A renewed NCSP was introduced on 1 December 2017 that included a change from 2-yearly Pap tests for the target age group 20–69 to 5-yearly human papillomavirus (HPV) tests, followed by a liquid-based cytology (LBC) test if oncogenic (cancer-causing) HPV is found, for the target age group 25–74.
This is the fifth report to present data for the renewed NCSP. Data included in this report are for the calendar years 2018, 2019, 2020, 2021, and 2022.
Terminology
This report uses the terms ‘participants’ and ‘invitees’ when referring to data collected under the NCSP. These data are not restricted by sex or gender, with all cervical screening participants and invitees included in these data. For NCSP data, participants and invitees may include women, transgender men, intersex people, and non-binary people.
This report uses the term 'women' to mean ‘female' when referring to cancer incidence data and cancer mortality data as these data sources are based on sex assigned at birth. However, it should be noted that some people may not identify with this term.
Recruitment
Participation and coverage in the renewed NCSP can now be measured as 5 years of data are available. Participation is restricted to only screening HPV tests, whereas coverage is not restricted in this way, and is a better indication of overall participation in cervical screening.
Over the 5 years 2018–2022, more than 4.7 million participants aged 25–74 had a screening HPV test (primary screening or 12-month repeat HPV test). Participation has been determined to be 68% of the eligible population.
Over the 5 years 2018–2022, more than 5.2 million participants aged 25–74 had an HPV or LBC test for any reason. Coverage has been determined to be 77% of the eligible population.
Screening
Screening HPV test positivity is the proportion of valid primary screening HPV tests that detected oncogenic HPV. In 2022, for participants aged 25–74:
- positivity was 2% for oncogenic HPV 16 and 18 (the two types of HPV that cause most cervical cancers)
- positivity was 8% for oncogenic HPV other than 16 and 18
- positivity was 10% for any oncogenic HPV type.
Assessment
Participants considered at higher risk of a significant cervical abnormality are referred for colposcopy, which is the examination of the cervix using a magnifying instrument called a colposcope and is the first step in assessment.
In 2021, of the participants aged 25–74 at higher risk of a significant cervical abnormality, 63% had a colposcopy within 3 months. Median time to colposcopy was 56 days.
Diagnosis
Detection of high-grade abnormalities provides an opportunity for treatment before possible progression to cervical cancer.
In 2022, for every 1,000 participants screened, 14 participants had a high-grade abnormality detected by histology. In contrast, for every 1,000 participants screened, 1 had a cervical cancer detected. This reflects that the aim of cervical screening is not to detect cervical cancer, but to prevent it through the detection of high-grade abnormalities.
Outcomes
In 2019, 869 women aged 25–74 were diagnosed with cervical cancer, which is 11 new cases per 100,000 women in the population.
In 2021, 179 women aged 25–74 died from cervical cancer, which is 2 deaths per 100,000 women in the population.
Aboriginal and Torres Strait Islander participants
Cervical screening outcomes are reported for Aboriginal and Torres Strait Islander participants for HPV screening test positivity, colposcopy rate, and high-grade cervical abnormality detection rate at the national level for the first time in this report.
In 2022, for Aboriginal and Torres Strait Islander participants aged 25–74 positivity was:
- 2% for oncogenic HPV 16 and 18 (the two types of HPV that cause most cervical cancers)
- 12% for oncogenic HPV other than 16 and 18
- 14% for any oncogenic HPV type.
In 2021, of the Aboriginal and Torres Strait Islander participants aged 25–74 at higher risk of a significant cervical abnormality, 51% had a colposcopy within 3 months.
In 2022, for every 1,000 Aboriginal and Torres Strait Islander participants aged 25–74 screened, 20 had a high-grade abnormality detected, providing an opportunity for treatment prior to any possible progression to cervical cancer.
In 2015–2019, 167 Aboriginal and Torres Strait Islander women aged 25–74 were diagnosed with cervical cancer. After adjusting for age, incidence among Aboriginal and Torres Strait Islander women was 2.1 times the rate of non-Indigenous women.
In 2017–2021, 58 Aboriginal and Torres Strait Islander women aged 25–74 died from cervical cancer. After adjusting for age, mortality among Aboriginal and Torres Strait Islander women was 3.5 times the rate of non-Indigenous women.
Summary
1. Prevention of cervical cancer through organised cervical screening
2. National Cervical Screening Program
3. Performance indicator monitoring
Recruitment
- Performance Indicator 1: Participation
- Performance Indicator 2: Response to invitation
- Performance Indicator 3: Rescreening
Screening
- Performance Indicator 4: Screening results
- Performance Indicator 5: Correlation of screening results
- Performance Indicator 6: Screening HPV test positivity
- Performance Indicator 7: Cervical cancer diagnosed after a low risk screening test result
- Performance Indicator 8: LBC test in self-collection participants positive for oncogenic HPV (not 16/18)
- Performance Indicator 9: Colposcopy in self-collection participants positive for oncogenic HPV 16/18
- Performance Indicator 10: Adherence to recommendation for follow-up
- Performance Indicator 11: Follow-up results
Assessment
- Performance Indicator 12: Colposcopy rate
- Performance Indicator 13: Time to colposcopy
- Performance Indicator 14: Biopsy rate
- Performance Indicator 15: Yield of high-grade abnormalities on biopsy among people who attend colposcopy after higher risk screening results
- Performance Indicator 16: Positive predictive value of colposcopy
Diagnosis
- Performance Indicator 17a: High-grade cervical abnormality detection rate
- Performance Indicator 17b: Cervical cancer detection rate
Outcomes
- Performance Indicator 18: Cervical cancers diagnosed by time since last screen
- Performance Indicator 19: Incidence of cervical cancer
- Performance Indicator 20: Mortality from cervical cancer
4. Cervical screening outcomes for Aboriginal and Torres Strait Islander participants
Appendix A: Additional data tables
- A1 Participation
- A2 Response to invitation
- A4 Screening results
- A5 Correlation
- A6 Screening HPV test positivity
- A8 LBC test in self-collection participants positive for oncogenic HPV (not 16/18)
- A9 Colposcopy in self-collection participants positive for oncogenic HPV 16/18
- A10 Adherence to recommendation for follow-up
- A11 Follow up results
- A12 Colposcopy rate
- A13 Time to colposcopy
- A14 Biopsy rate
- A15 Yield of high-grade abnormalities on biopsy among people who attend colposcopy after higher risk screening results
- A16 Positive predictive value of colposcopy
- A17a High-grade cervical abnormality detection rate
- A17b Cervical cancer detection rate
- A19 Incidence of cervical cancer
- A20 Mortality from cervical cancer
Appendix B: HPV vaccination coverage
Appendix C: Data sources
Appendix D: Classifications
Appendix E: Statistical methods
End Matter: Acknowledgments; Abbreviations; Symbols; Glossary; References; List of tables; List of figures; List of boxes; Related material; Data