Kidney and urinary diseases
Key points
- In 2022, kidney & urinary diseases accounted 2.3% (7,179 DALY) of total burden, 3.4% (5,436 YLL) of fatal burden and 1.1% (1,743 YLD) of non-fatal burden among First Nations people.
- Kidney & urinary diseases was the 13th leading cause of total burden, the 10th leading cause for fatal burden and the 15th leading cause of non-fatal burden among First Nations people in 2022.
- Chronic kidney disease (CKD) was the largest contributor to burden due to kidney & urinary diseases, accounting for 94% of the total burden.
- Three-quarters (76%) of the burden due to kidney & urinary diseases was fatal burden, the majority of which was due to CKD (96% of fatal burden for kidney & urinary diseases).
- The total burden due to kidney & urinary diseases was higher for First Nations females than males (54% and 46%, respectively).
- The majority (84%) of non-fatal kidney & urinary burden among First Nations people occurred in those aged 45 and over.
- Between 2011 and 2022, the age-standardised rate of total burden due to kidney & urinary diseases for First Nations people decreased by 7.3%.
- In 2022, the age-standardised rate of burden due to kidney & urinary diseases for First Nations people was 4.9 times the rate for non-Indigenous Australians.
The kidney & urinary disease group includes chronic kidney disease (CKD), enlarged prostate, interstitial nephritis, kidney stones and the residual group ‘other kidney & urinary diseases’.
It is important to note that the results provided here represent the direct impact of kidney & urinary diseases. CKD, in particular impaired kidney function, is an important risk factor for other diseases, such as coronary heart disease. These indirect impacts are not included here, but are instead included in the disease group where the disease effects are more immediate, for example, in cardiovascular diseases. Indirect effects can be estimated in some cases by considering impaired kidney function as a risk factor for other diseases, which will be presented in a future risk factor release.
Chronic kidney disease (CKD) is a substantial health problem in First Nations people. CKD among First Nations people is multifactorial, and many of its risk factors are associated with social disadvantage and accelerated lifestyle change (Hoy et al. 2016). First Nations people, particularly those living in remote communities, are at greater risk of developing CKD, and early kidney damage is common (Chaturvedi et al. 2021). CKD is often associated with low birthweight and reduced kidney functioning through inflammation and infection, and other morbidities such as diabetes and high blood pressure. Levels of CKD among First Nations people are high, with prevalence rates twice those of non-Indigenous Australians (AIHW 2020).
Although end-stage kidney disease – the most severe form of CKD, where a person requires dialysis or a kidney transplant to survive – usually occurs in older age, in First Nations people it occurs more often in middle age (age 50 and under) (AIHW 2020). The need for dialysis, which involves strict treatment protocols and frequent treatment – normally 4–5 hour sessions 3 times per week for in-centre dialysis – has an extensive impact on health, lifestyle and social and emotional wellbeing, especially among First Nations people living in rural and remote areas, who often need to relocate to access treatment (Rix et al. 2014; Scholes-Robertson et al. 2022; ANZDATA 2025).
How much burden do kidney & urinary diseases contribute?
Overall, kidney & urinary diseases was the 13th leading cause of total burden, the 10th leading cause of fatal burden and the 15th leading cause of non-fatal burden among First Nations people in 2022.
In 2022, kidney & urinary diseases accounted 2.3% (7,179 DALY) of total burden, 3.4% (5,436 YLL) of fatal burden and 1.1% (1,743 YLD) of non-fatal burden among First Nations people.
CKD was the largest contributor to burden due to kidney & urinary diseases, accounting for 94% of the total burden.
To explore the contribution of total, non-fatal and fatal burden for each disease group, see the interactive data visualisation: Dashboard 1: Burden of disease in Australia.
What are the differences between fatal and non-fatal burden?
About three-quarters (76%) of burden due to kidney & urinary diseases was fatal burden (Figure 1a), the majority of which was due to CKD (96% of fatal burden for kidney & urinary diseases). Premature death was responsible for the majority of burden across all kidney & urinary diseases, except for enlarged prostate where only 12% of the burden was fatal (Figure 1a).
Figure 1a: Kidney & urinary diseases burden (DALY), diseases by burden type, First Nations people, 2022
Note: The residual cause ‘Other kidney & urinary diseases’ includes a range of diseases such as cystitis, stress incontinence and acute prostatitis. See the Australian Burden of Disease Study: methods and supplementary material 2018 for a full list of ICD-10 codes.
Source: AIHW First Nations Burden of Disease Database
How does burden differ by sex?
There were differences in burden due to kidney & urinary diseases between males and females, with DALY and YLL rates higher among First Nations females than males. YLD rates were the same for males and females (Table 1).
Sex | DALY | YLD | YLL |
|---|---|---|---|
Males | 6.5 | 1.7 | 4.8 |
Females | 7.6 | 1.7 | 5.8 |
Persons | 7.0 | 1.7 | 5.3 |
Source: AIHW First Nations Burden of Disease Database
Overall, females experienced more of the burden due to kidney & urinary diseases than males (54% and 46%, respectively), but this varied by disease (Figure 1b). First Nations females experienced a larger proportion of burden due to CKD (55%), interstitial nephritis (61%), and kidney stones (90%), while First Nations males experienced a larger proportion of the burden due to other kidney & urinary diseases (66%) and all of the burden due to enlarged prostate.
Figure 1b: Kidney & urinary diseases burden (DALY), diseases by burden type and sex, First Nations people, 2022
Note: The residual cause ‘Other kidney & urinary diseases’ includes a range of diseases such as cystitis, stress incontinence and acute prostatitis. See the Australian Burden of Disease Study: methods and supplementary material 2018 for a full list of ICD-10 codes.
Source: AIHW First Nations Burden of Disease Database
How does burden differ by age?
The number of DALY due to kidney & urinary diseases was highest among those aged 45–64, while the age-specific DALY rates were highest among those aged 75 and over, and 65–74. The numbers and rates of DALY were lowest for those aged under 25. A similar pattern was evident for age-specific YLL and YLD rates (Table 2).
Age group | Number of DALY | DALY rate | YLD rate | YLL rate |
|---|---|---|---|---|
Under 5 | 32 | 0.3 | — | 0.3 |
5–14 | 7 | — | — | — |
15–24 | 46 | 0.2 | 0.1 | 0.1 |
25–44 | 1,033 | 3.9 | 1.0 | 3.0 |
45–64 | 3,268 | 18.4 | 5.0 | 13.4 |
65–74 | 1,687 | 41.3 | 9.6 | 31.7 |
75 and over | 1,105 | 67.4 | 10.8 | 56.6 |
Total | 7,179 | 7.0 | 1.7 | 5.3 |
— Zero or rounded to zero
Source: AIHW First Nations Burden of Disease Database
Non-fatal burden
CKD can be split into end-stage and non-end-stage disease. End-stage kidney disease is responsible for most (90%) of the total burden and almost all (96%) of the fatal burden due to kidney & urinary diseases. This section therefore focuses on how the non-fatal burden is distributed by disease and age.
CKD accounted for 90% of the non-fatal burden due to kidney & urinary diseases experienced by First Nations people in 2022. CKD can be split into end-stage and non-end-stage disease, which, respectively, accounted for 71% and 19% of the non-fatal burden due to kidney & urinary diseases (Figure 2).
Figure 2: Contribution of individual causes to kidney & urinary diseases non-fatal burden (YLD), First Nations people, 2022
Notes
- Percentage labels are not shown for disease groups contributing less than 4.5% of burden.
- The residual cause ‘Other kidney & urinary diseases’ includes a range of diseases such as cystitis, stress incontinence and acute prostatitis. See the Australian Burden of Disease Study: methods and supplementary material 2018 for a full list of ICD-10 codes.
Source: AIHW First Nations Burden of Disease Database
How does non-fatal burden differ by age?
The majority (84%) of non-fatal kidney & urinary burden among First Nations people occurred in those aged 45 and over. End-stage CKD was the largest cause of non-fatal burden among those aged 45–64, accounting for more than three-quarters (77%) of the non-fatal burden. End-stage CKD was also the largest cause of non-fatal burden for those aged 65 and over, accounting for over half (58%) of the non-fatal burden.
Figure 3: Contribution of individual causes to kidney & urinary diseases non-fatal burden (YLD), by age group, First Nations people, 2022
Notes
- Proportions in the under 5, 5–14 and 15–24 age groups should be treated with caution, due to underlying small numbers.
- The residual cause ‘Other kidney & urinary diseases’ includes a range of diseases such as cystitis, stress incontinence and acute prostatitis.
Source: AIHW First Nations Burden of Disease Database
To explore the contribution of fatal and non-fatal burden to the leading causes of the top 5 disease groups see the interactive data visualisation: Dashboard 7: Top disease groups across the stages of life.
How has the burden changed over time?
Between 2011 and 2022, the age-standardised rate of total burden due to kidney & urinary diseases for First Nations people decreased slightly from 13 to 12 DALY per 1,000 people—a reduction of 7.3% (Figure 5).
This was driven by a decrease in the non-fatal burden (a decrease of 1.1 YLD per 1,000). The decrease seen in non-fatal burden was mainly due to a decrease in the burden of CKD (of 0.8 YLD per 1,000).
Figure 4: Change between 2011 and 2022 in the age-standardised total (DALY), fatal (YLL), and non-fatal (YLD) burden rate (per 1,000 people), kidney & urinary diseases, First Nations people
Source: AIHW First Nations Burden of Disease Database
For non-Indigenous people, the age-standardised rate of total burden due to kidney & urinary diseases remained stable between 2011 and 2022 (2.6 and 2.5 DALY per 1,000 people). A similar picture was evident for the age-standardised non-fatal (1.0 and 0.9 YLD per 1,000 people) and fatal (1.6 YLL per 1,000 people, respectively) burden rates over the same period (see Figure 7 in Gap in disease burden section).
To explore the changes over time in the DALY, YLD, and YLL for First Nations people in each disease group, see the interactive data visualisation: Dashboard 3: Comparisons over time.
Comparisons with non-Indigenous Australians
In 2022, the age-standardised rate of burden due to kidney & urinary diseases for First Nations people was 4.9 times the rate for non-Indigenous Australians (age-standardised rates of 12.3 and 2.5 DALY per 1,000 people, respectively) (Table 2).
The largest absolute difference in DALY rates between First Nations people and non-Indigenous Australians was observed for CKD (rate difference of 9.7 DALY per 1,000 people). CKD also accounted for the largest relative difference in age-standardised DALY rates between First Nations people and non-Indigenous Australians (rate ratio of 5.9).
Causes | First Nations rate (DALY per 1,000 people) | Non-Indigenous rate (DALY per 1,000 people) | Rate ratio | Rate difference |
|---|---|---|---|---|
Chronic kidney disease | 11.6 | 2.0 | 5.9 | 9.7 |
Interstitial nephritis | 0.2 | — | 4.8 | 0.1 |
Kidney stones | 0.1 | — | 2.3 | — |
Enlarged prostate | 0.3 | 0.4 | 0.8 | -0.1 |
Other kidney & urinary diseases | 0.1 | 0.1 | 1.4 | — |
Total kidney & urinary | 12.3 | 2.5 | 4.9 | 9.8 |
— Zero or rounded to zero
Source: AIHW First Nations Burden of Disease Database
To explore the gap in disease burden between First Nations people and non-Indigenous Australians, see the interactive data visualisation: Dashboards 6a and 6b: Gap in health outcomes.
AIHW (Australian Institute of Health and Welfare) 2020 Profiles of Aboriginal and Torres Strait Islander people with kidney disease, AIHW, Australian Government, accessed 9 February 2026.
ANZDATA (Australia and New Zealand Dialysis and Transplant Registry) 2025 ANZDATA 48th Annual Report 2025 (Data Survey 2024), ANZDATA, accessed 10 February 2026.
Chaturvedi S, Ullah S, LePage AK & Hughes JT (2021) Rising Incidence of End-Stage Kidney Disease and Poorer Access to Kidney Transplant Among Australian Aboriginal and Torres Strait Islander Children and Young Adults, Kidney International Reports, 6:1704-1710, doi:10.1016/j.ekir.2021.02.040.
Hoy WE, Mott SA & McDonal SP (2016) An expanded nationwide view of chronic kidney disease in Aboriginal Australians, Nephrology, 21(11): 916-922, doi:10.1111/nep.12798.
Rix EF, Barclay L, Stirling J, Tong A & Wilson S (2014) ‘Beats the alternative but it messes up your life’: Aboriginal people’s experience of haemodialysis in rural Australia, BMJ Open, 4: e005945, doi:10.1136/bmjopen-2014-005945.
Scholes-Robertson N, Gutman T, Howell M, Craig JC, Chalmers R & Tong A (2022) Patients’ Perspectives on Access to Dialysis and Kidney Transplantation in Rural Communities in Australia, Kidney International Reports, 7: 591-600, doi:10.1016/j.ekir.2021.11.010