Performance indicator 7a: Invasive breast cancer incidence
Summary
- In 2021, 18,853 new cases of breast cancer were diagnosed in women in Australia which is an incidence rate of 145.7 new cases per 100,000 women.
- In 2021, 11,540 new cases of breast cancer were diagnosed in women aged 50–74 in Australia which is an incidence rate of 319.3 new cases per 100,000 women.
- Breast cancer incidence for women aged 50–74 decreased as remoteness increased.
- Breast cancer incidence in women aged 50–74 decreased as socioeconomic disadvantage increased.
Definition
The number of new cases of invasive breast cancer in women aged 50–74 per 100,000 resident female population in a calendar year.
Rationale
Incidence data provide information about the number of new cases of invasive breast cancer in the population, which is an indicator of the program’s performance against its aim to detect unsuspected breast cancer in women through organised screening.
Guide to interpretation
Incidence data include both screen-detected breast cancers (detected through BreastScreen Australia) and breast cancers detected outside BreastScreen Australia.
Incidence of invasive breast cancer by state and territory, remoteness area, socioeconomic status and Indigenous status is reported over a 5-year (instead of a 12-month) period.
Invasive breast cancer incidence data are reported per 100,000 females in the population.
Lower breast cancer incidence is better.
The Australian Cancer Database (ACD) currently contains data on all cases of cancer diagnosed from 1982 to 2021 for all states and territories.
The most recent invasive breast cancer incidence data are for new cases diagnosed in 2021 and estimates to 2025.
Results
In 2021, the latest year of national data available in the Australian Cancer Database, there were 18,853 new cases of breast cancer diagnosed in women of all ages in Australia, which is 145.7 new cases per 100,000 women in the population (123.1 new cases per 100,000 women after adjusting for age to allow comparison over time or across population groups).
Of these 18,853 new cases, 11,540 (61.2%) occurred in women aged 50–74 (the target age group for BreastScreen Australia), which is equivalent to 319.3 new cases per 100,000 women aged 50–74 (311.0 new cases per 100,000 women aged 50–74 after adjusting for age to allow comparison over time or across population groups).
Box 7.1: Estimated incidence to 2025
Incidence data are estimated to the current year of reporting, based on 2012–2021 incidence data (note that actual incidence data for 2022–2025 may differ from estimated data for these years due to current and ongoing program or practice changes).
In 2025, it is estimated that there will be 20,129 new cases of breast cancer in Australian women, equivalent to 122.3 new cases per 100,000 women when age standardised.
Of these 20,129 new cases, it is estimated that 11,900 will occur in women aged 50–74, equivalent to 307.8 new cases per 100,000 women when age-standardised.
Box 7.2: Invasive breast cancer detected through BreastScreen Australia
Almost half (48.5%) of all invasive breast cancer cases diagnosed in 2021 in women aged 50–74 were detected through BreastScreen Australia (35.2% for women aged 40 and over).
Incidence by age
In 2021, breast cancer incidence increased with increasing age, from 129.4 new cases per 100,000 women aged 40–44 to 427.0 per 100,000 women aged 70–74 (Figure 7.1).
Figure 7.1: Incidence of breast cancer in women, by age group, 2021
This line chart shows that breast cancer incidence increased with increasing age, from 129.4 for women aged 40–44 to 427.0 for women aged 70–74.
| Age group (years) | Incidence rate (per 100,000 women) |
|---|---|
| 40–44 | 129.4 |
| 45–49 | 204.1 |
| 50–54 | 259.2 |
| 55–59 | 258 |
| 60–64 | 317.2 |
| 65–69 | 372.4 |
| 70–74 | 427 |
Source: AIHW Australian Cancer Database 2021. Data for this figure are available in Table A7.1
Incidence by histological type
Invasive breast cancers by histological type are shown in Table 7.1.
Note that histological groupings for breast cancer have changed from previous reports, in line with the histology framework for breast cancer in the December 2024 release of Cancer data in Australia (AIHW 2024b).
In 2021, for women aged 50–74, ductal carcinomas were the most common breast cancer type, comprising 83.9% of all breast cancers; lobular carcinomas were the second most common, at 13.4% of all breast cancers.
Overall, carcinomas comprise 99.4% of all breast cancers, with sarcomas, other cancers, and unclassifiable cancers making up the remainder (Table 7.1).
Histological type of breast cancer | New cases | Crude rate | Percentage of breast cancers |
|---|---|---|---|
1: Carcinomas | 11,474 | 317.4 | 99.4 |
1.1: Ductal carcinomas | 9,685 | 267.9 | 83.9 |
1.2: Lobular carcinomas | 1,551 | 42.9 | 13.4 |
1.3: Papillary carcinomas | 138 | 3.8 | 1.2 |
1.4: Salivary gland-type carcinomas | 16 | 0.4 | 0.1 |
1.5: Neuroendocrine neoplasms | 5 | 0.1 | 0.0 |
1.6: Epithelial-myoepithelial carcinomas | 1 | 0.0 | 0.0 |
1.7: Unclassifiable carcinomas | 78 | 2.2 | 0.7 |
2: Sarcomas | 13 | 0.4 | 0.1 |
3: Other cancers | 16 | 0.4 | 0.1 |
4: Unclassifiable cancers | 37 | 1.0 | 0.3 |
Total | 11,540 | 319.3 | 100.0 |
Notes:
- ‘Crude rate’ is the number of new cases of breast cancer per 100,000 women.
- The histology codes that comprise each breast cancer group appear in Table Appendix B1.
Source: AIHW Australian Cancer Database 2021.
Incidence by state and territory
In 2017–2021, the incidence of breast cancer for women aged 50–74 varied between 255.9 and 351.0 new cases per 100,000 women. Note that data for the least-populated jurisdictions are subject to variation due to smaller numbers, even with 5 years of combined data.
Incidence by remoteness area
In 2017–2021, breast cancer incidence for women aged 50–74 decreased as remoteness increased.
After adjusting for age, breast cancer incidence in women aged 50–74 was highest for those living in Major cities at 316.5 new cases per 100,000 women and lower for those living in Inner regional areas and Outer regional areas at 313.6 and 306.9 new cases per 100,000 women, respectively.
The lowest incidence rates were for women living in Remote and Very remote areas at 275.7 and 257.3 new cases per 100,000 women, respectively (Figure 7.2).
Incidence by socioeconomic area
In 2017–2021, breast cancer incidence for women aged 50–74 decreased as socioeconomic disadvantage increased.
After adjusting for age, breast cancer incidence in women aged 50–74 was highest for women residing in least disadvantaged socioeconomic areas at 336.0 new cases per 100,000 women; thereafter, it decreased with increasing socioeconomic disadvantage and was lowest for women residing in most disadvantaged socioeconomic areas at 299.2 new cases per 100,000 women (Figure 7.2).
Figure 7.2: Incidence of breast cancer in women aged 50–74, by remoteness area and socioeconomic area, 2017–2021
These side-by-side vertical bar charts show incidence was lowest for women in Very remote areas and for women in most disadvantaged socioeconomic areas.
Incidence trends
Prior to the introduction of BreastScreen Australia in 1991, the age‑standardised incidence rate of breast cancer had increased from 183 new cases per 100,000 women aged 50–74 in 1982 to 221 in 1990.
Following the introduction of BreastScreen Australia, the age‑standardised incidence rate of breast cancer increased from 239 new cases per 100,000 women aged 50–74 in 1991 to 312 in 2001. From 2001 to 2012, the rate per 100,000 women remained relatively steady at around 300, before increasing to 330 in 2014, and remaining relatively steady thereafter until 2020 when it decreased to 300, before rising slightly in 2021 to 311 new cases per 100,000 women aged 50–74 (Figure 7.3).
Figure 7.3: Incidence of breast cancer in women aged 50–74, 1982 to 2021
This combined bar/line chart shows breast cancer incidence increased from 183 new cases in 1982 to 311 new cases in 2021.
Survival from invasive breast cancer
Survival in this report refers to ‘relative survival’; which is the probability of being alive for a given amount of time after a cancer diagnosis, compared with the general population, and reflects the impact of a cancer diagnosis. The source of survival data is the 2021 Australian Cancer Database which includes data from the National Death Index on deaths (from any cause) that occurred up to 31 December 2021, which were used to determine which people with cancer had died and when this occurred.
In 2017–2021, women diagnosed with breast cancer in Australia had a 92.7% chance of surviving for 5 years, compared with their counterparts in the general population. For the target age group (50–74), 5‑year relative survival was 94.3%.
Five-year relative survival by age
In 2017–2021, women aged between 40 and 74 had the highest chance of surviving for 5 years at between 94% and 95%, Women aged less than 40 had lower 5-year relative survival at around 90%, while women over 74 had the lowest chance of surviving for 5 years, falling below 90% (Figure 7.4).
Figure 7.4: Five-year relative survival from breast cancer in women, by age group, 2017–2021
This line chart shows that women aged between 40 and 74 had the highest chance of surviving for 5 years at between 94% and 95%.
| Age group (years) | Survival (per cent) |
|---|---|
| 40–44 | 93.6 |
| 45–49 | 94.8 |
| 50–54 | 94.4 |
| 55–59 | 94.1 |
| 60–64 | 94.4 |
| 65–69 | 94.6 |
| 70–74 | 94.1 |
| 75+ | 85.1 |
Relative survival was calculated with the period method, using the period 2017–2021 (Brenner & Gefeller 1996).
Source: AIHW Australian Cancer Database 2021. Data for this figure are available in Table A7.7.
Five-year relative survival trends
Between 1987–1991 and 2017–2021, 5-year relative survival increased from 75.1% to 94.3% for women who were diagnosed with breast cancer when aged 50–74 (Figure 7.5).
Figure 7.5: Trends in 5-year relative survival from breast cancer in women aged 50–74, 1987–1991 to 2017–2021
This line chart shows between 1987–1991 and 2017–2021, 5-year relative survival increased from 75.1% to 94.3%.
| Years | Survival (per cent) |
|---|---|
| 1987–1991 | 75.1 |
| 1992–1996 | 82.3 |
| 1997–2001 | 87.8 |
| 2002–2006 | 90.4 |
| 2007–2011 | 91.6 |
| 2012–2016 | 93.1 |
| 2017–2021 | 94.3 |
Relative survival was calculated with the period method, using the period 2017–2021 (Brenner & Gefeller 1996)
Source: Australian Cancer Database 2021. Data for this figure are available in Table A7.8.
Conditional survival
Conditional survival is the probability of surviving a given number of years provided that an individual has already survived a specified amount of time after diagnosis.
In 2017–2021, when women aged 50–74 were first diagnosed with breast cancer, they had a 94.3% chance of surviving for at least 5 years after diagnosis compared with the general population (Figure 7.6). For those women who had already survived 5 years after being diagnosed with breast cancer, the chance of surviving for at least another 5 years (5-year conditional relative survival) was around 96%.
Figure 7.6: Relative survival at diagnosis and 5‑year conditional survival from breast cancer in women aged 50–74, 2017–2021
This line chart shows that, once a woman has survived for at least 5 years, survival is very high at around 96%.
Prevalence of invasive breast cancer
Prevalence is the number of people alive after a diagnosis of cancer. It is related to incidence and survival: if incidence and survival are both high, prevalence will be high; if incidence and survival are both low, prevalence will be low.
The source of prevalence data is the 2021 Australian Cancer Database which includes data from the National Death Index on deaths (from any cause) that occurred up to 31 December 2021, which were used to determine which people with cancer had died and when this occurred. Individuals who have been diagnosed with cancer and are still alive contribute to prevalence data.
At the end of 2021, there were 53,236 women aged 50–74 alive who had been diagnosed with breast cancer in the previous 5 years and 96,054 alive who had been diagnosed in the previous 10 years (Table 7.2).
Prevalence by age is shown in Figure 7.7.
Age group (years) | 5 year prevalence | 10 year prevalence |
|---|---|---|
<40 | 3,036 | 3,906 |
40–44 | 3,712 | 5,172 |
45–49 | 6,586 | 9,973 |
50–54 | 9,839 | 16,212 |
55–59 | 9,553 | 18,185 |
60–64 | 10,675 | 19,505 |
65–69 | 11,238 | 20,417 |
70–74 | 11,931 | 21,735 |
75–79 | 8,094 | 16,483 |
80–84 | 5,147 | 10,284 |
85+ | 4,872 | 9,382 |
50–74 | 53,236 | 96,054 |
All ages | 84,683 | 151,254 |
Note: Prevalence refers to the number of living people previously diagnosed with cancer, not the number of cancer cases.
Source: AIHW Australian Cancer Database 2021.
Figure 7.7: Prevalence of breast cancer in women, by age group, end of 2021
This grouped vertical bar chart shows prevalence is highest for women aged 60–79.
| Age group (years) | 5-year prevalence | 10-year prevalence |
|---|---|---|
| 40–44 | 3712 | 5172 |
| 45–49 | 6586 | 9973 |
| 50–54 | 9839 | 16212 |
| 55–59 | 9553 | 18185 |
| 60–64 | 10675 | 19505 |
| 65–69 | 11238 | 20417 |
| 70–74 | 11931 | 21735 |
Source: AIHW Australian Cancer Database 2021.
AIHW (2024b) Cancer data in Australia, AIHW, Australian Government, accessed 15 August 2024.
Brenner H & Gefeller O 1996. An alternative approach to monitoring cancer patient survival. Cancer 78(9):2004–10.